Zoladex in the Treatment of Endometriosis: A Randomized Comparison with Danazol
Friday, December 5th, 2008Endometriosis, a common gynecologic condition affecting 2.5-15% of women of reproductive age, depends on cyclical ovarian steroids, especially estradiol (E2), and is associated with debilitating symptoms. The primary sequelae of endometriosis include pelvic pain and endometrial implants, as well as dysmenorrheal and dyspareunia. The relationships between endometriosis and infertility is well accepted and documented. The goals of therapy include relief of symptoms, resolution of existing lesions, and prevention of new lesions…